Tuberculosis Definition: A communicable chronic granulomatous disease caused by mycobacterium tuberculosis. Characterized by the formation of tubercular granuloma Clinically: insidious, low-grade fever and remittent, night sweats, sputum with or without hemoptysis,pleuritic pain capable of being transmitted by infection /A communicable disease is one that can be passed on to other people.characterized by periods of diminished severity. Etiology: Pathogen – Mycobacterium tuberculosis M. hominis M. bovis M. avium-intracellulare (few but common in HIV + individual) Transmitting route Respiratory （airborne droplet） Intestinal Skin wound Mycobacterium tuberculosis (MTB) is a pathogenic bacteria species in the family mycobacteriaceae and the causative agent of most cases of tuberculosis (TB). First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface (primarily mycolic aci...