Cell injury-3

In previous discussion we have discussed
  1. Definition and explanation of cell injlury
  2. Mechanism of injury
  3. Initiate Step- Membrane Injury
  4. Normal cell VS Damaged cell
  5. Mitochondrial Dysfunction in Cell Injury
  6. Over Oxygen Free Radical Production
  7. Final step of cell injury (High Concentration of Cytosolic Free Calcium)
So now we will continue our discussion with

Steps of injury:

This is the relation of 3 changes in injury. Membrane injury often is earliest event, and ATP depletion is the beginning of most injury. So we take the Membrane injury as key step in injury. If membrane change is not so severe and short, the injury can be reversible. But membrane injury often trigger over free radicals production and high intracellular free calcium. That will aggravate the cell injury. Over free radicals production is also commonest event in injury. We have know that many harmful stimulators can cause that. So we take this change as basic step in injury. Once high intracellular free calcium happen, the cell is hard to recover. We take it as final step in injury. Note that these two consequent steps can injury membrane further.  What the doctor should do is to block such a pathological  causation coiling procedure.
https://www.hanxinclinic.com/index.php/2019/12/10/cell-injury-3/

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